Bum Ju Lee
Korea Institute of Oriental Medicine, South Korea
Title: The relationship of nutritional component and peptic ulcer disease
Biography
Biography: Bum Ju Lee
Abstract
Statement of the Problem: Peptic ulcer disease is a common disease worldwide and has been a significant effect on morbidity and mortality over the past two centuries. Peptic ulcer disease was categorized into duodenal ulcer, gastric and stomach ulcer, and unspecified peptic ulcer. Until now, several studies have reported that the intake of nutritional components is associated with peptic ulcer disease. However, the association of peptic ulcer disease with nutrition components remains to be fully understood.
Purpose: The purpose of this study is to examine the association of nutritional components with peptic ulcer disease in Korean population.
Methodology & Theoretical Orientation: A total of 6,323 subjects (2,808 men and 3,515 women) were participated in this study. We obtained the data from the First Korea National Health and Nutrition Examination Survey (KNHANES I). In the crude analysis and the analyses adjusted for gender and age, binary logistic regression was performed to identify association between the peptic ulcer patients and the normal subjects.
Findings: In nutritional components, fiber was significantly associated with peptic ulcer disease (p = 0.0003, OR = 1.19 [1.082-1.31]), and this association remained significant after adjusting for age and gender (adjusted p = 0.033, adjusted OR = 1.108 [1.008-1.218]). In both crude and adjusted analyses, peptic ulcer disease was related to calcium (adjusted p = 0.039, adjusted OR = 1.117 [1.006-1.240]) and sodium (adjusted p = 0.013, adjusted OR = 1.134 [1.027-1.253]). Although vitamins (A, B2, and C), carotene, and niacin were associated with peptic ulcer disease, these associations disappeared after adjusting for gender and age.
Conclusion & Significance: Fiber, calcium, and sodium were significantly associated with peptic ulcer disease in Korea, regardless of gender and age.